| A Flexible, High-throughput, Cost Effective Robotics Solution for HTS |
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Presentation: P03039 Session: Robotic Screening & Automation Technologies - Poster SessionWilliam Goode, John Munro and Adam Hill, Novartis Institutes for Biomedical Research Presenting Author: William Goode, Novartis Institutes for Biomedical Research - USA Lead finding organizations have invested substantial capital in High Throughput Screening (HTS) technologies over the last decade. As a result, Laboratory automation has evolved from simple small robot centric systems to advanced industrialized factories. As research organizations begin to scrutinize large capital investments, companies are forced to re-evaluate their approach to screening and the subsequent costs. The Lead Discovery Center at NIBR in Cambridge, MA has implemented a screening platform that falls between the small workstation robotics and the industrialized screening approach. These HTS workcells are flexible, assay independent systems which are simple to configure and operate. The relatively low integration cost has allowed NIBR to purchase multiple systems which operate in parallel. This strategy builds capacity and allows for multiple screening campaigns to be processed. The flexible nature of the systems allow them to be re-configured easily and thus maximizing the lifetime of the equipment for purposes beyond HTS. |