Presentation: P03022

High Throughput Screening laboratories have been successfully automating assays to achieve higher throughput. To date only a small number of labs have been successfully able to go to even higher density formats, i.e., 1536-well microplates, due to the lack of precise liquid handling systems, homogeneous robust detection assays and high density detection equipment. Examples shown here will demonstrate that the LANCE™ cAMP assay, which allows for the direct measurement of receptor mediated adenylyl cyclase activation/inhibition in G-protein coupled receptors, the Evolution™ P3 liquid handling system and the ViewLux™ CCD Imager, will give comparable results with excellent precision for both 384-well and 1536-well formats.

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