Presentation: P03027

The continuing emphasis on sample integrity has re-enforced the need to reduce the adverse effects that multiple freeze/thaw cycles can have on DMSO solubilized samples. A key technology in this area is single use 384-microtubes, allowing individual low-volume sample replicas to be cherry picked, thus avoiding the freeze/thaw cycle.

Whilst offering significant advantages for improved sample integrity, the relatively low picking rate for such microtubes has imposed a throughput bottleneck on downstream HTS processes. In addition, the move towards focused screening has led to an increase in required picking rates.

RTS has developed a high-speed, high-throughput multiple tube picking system (384 Multi-Pix™) that is able to pick and place over 100 microtubes in less than 4 seconds. This poster describes this picking system and demonstrates how this technology may be used to obtain the benefits of single use 384 tubes without suffering the throughput issues described.

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