Presentation: P03011

During the last few years, technical developments have dramatically changed the way cell-based assays could be implemented and used in Research and Development organizations. Developments of new cell lines and defined growth media as well as reagents such as specific antibodies, luminescent and fluorescent kits now allow the implementation of specific and sensitive biologically relevant cell-based assays. These changes combined with significant improvements of readers and automation systems able to handle high-throughput assays transformed cell-based assays into a critical tool that could be implemented at multiple stages during the life of a therapeutic molecule from discovery to development.

Although cell-based assays have moved into a modern era, cells are still grown and maintained like decades ago: MANUALLY. This step is now a significant bottleneck for many organizations where cell-based assays are a critical path. This presentation will review the rational to implement an automated cell culture workstation at Genentech, Inc. and move forward with the Tecan Cellerity™.

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